Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259716 | 0.80 | LCK (0.45) | LCKCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9261637 | 0.74 | ALOX15 (0.41) | LMNAMAPTCYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL9259471 | 0.74 | ALOX15 (0.41) | LMNAMAPTCYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL9258671 | 0.71 | SMN1; SMN2 (0.38) | MAPTCYP1A2CYP3A4SMN1; SMN2KMT2A | |
| SCHEMBL9259996 | 0.67 | HSP90AA1 (0.41) | MAPTCYP1A2SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL12189258 | 0.66 | LCK (0.55) | LCKCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9260914 | 0.66 | HSP90AA1 (0.41) | LMNAMAPTCYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL9259063 | 0.66 | HSP90AA1 (0.41) | LMNAMAPTCYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL14097068 | 0.65 | LCK (0.66) | LCKCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9255559 | 0.65 | MAPT (0.40) | MAPTNPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |