Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263157 | 0.82 | ALDH1A1 (0.44) | MAPTNR1H4KMT2ARAB9AMEN1 | |
| SCHEMBL9261637 | 0.80 | ALOX15 (0.41) | MAPTNR1H4ATMKDM4EHTT | |
| SCHEMBL9259471 | 0.80 | ALOX15 (0.41) | MAPTNR1H4ATMKDM4EHTT | |
| SCHEMBL9258671 | 0.72 | SMN1; SMN2 (0.38) | MAPTKMT2AMEN1NPSR1ATM | |
| SCHEMBL9259996 | 0.70 | HSP90AA1 (0.41) | MAPTKMT2AMEN1NPSR1KDM4E | |
| SCHEMBL9260914 | 0.69 | HSP90AA1 (0.41) | MAPTRAB9AKDM4ENPC1HTT | |
| SCHEMBL9259063 | 0.69 | HSP90AA1 (0.41) | MAPTRAB9AKDM4ENPC1HTT | |
| SCHEMBL9257311 | 0.65 | LCK (0.42) | MAPTKMT2ARAB9AMEN1KDM4E | |
| SCHEMBL5337947 | 0.60 | POLB (0.44) | MAPTKMT2ARAB9AMEN1NPSR1 | |
| SCHEMBL9001647 | 0.60 | ATM (0.72) | KMT2ARAB9AATMPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |