Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359626 | 0.82 | — | — | |
| SCHEMBL9260138 | 0.82 | — | — | |
| SCHEMBL9269994 | 0.80 | HTR6 (0.45) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9261619 | 0.79 | HTR6 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL9257440 | 0.76 | MEN1 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL9268994 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1 | |
| SCHEMBL9250734 | 0.73 | ALDH1A1 (1.00) | KDM4EALDH1A1 | |
| SCHEMBL8870395 | 0.73 | ALDH1A1 (1.00) | KDM4EALDH1A1 | |
| SCHEMBL3825291 | 0.73 | ALDH1A1 (1.00) | KDM4EALDH1A1 | |
| SCHEMBL3825287 | 0.73 | ALDH1A1 (1.00) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382670-A | Platelet activating factor antagonists | ABBOTT LABORATORIES (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0574494-A4 | INDOLES USEFUL AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0574494-A1 | INDOLES USEFUL AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992014732-A1 | INDOLES USEFUL AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-09-03 | — | — | WO | disclosed |
| EP-0499987-A1 | Platelet activating factor antagonists | ABBOTT LABORATORIES (US) | 1992-08-26 | — | — | EP | disclosed |
| US-5120749-A | Treatment of anaphylactic shock, respiratory distress syndrome, acute inflammation, delayed cellulosr immunity, parturtition, fetal lung maturation, and cellular differentiation | ABBOTT LABORATORIES (US) | 1992-06-09 | — | — | US | disclosed |