Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 5/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | NME4 | O00746 | 1/20 | 0.39 |
| ▸ | GCDH | Q92947 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257048 | 0.86 | ITGB3 (0.51) | F2RAB9AF10PRSS1NQO2 | |
| SCHEMBL9255355 | 0.83 | NR1H4 (0.49) | F2MAPTNPC1RAB9AF10 | |
| Hydrochloric Acid SCHEMBL9254391 | 0.79 | ST14 (0.54) | F2F10PRSS1ST14 | |
| SCHEMBL9254667 | 0.79 | F2 (0.41) | F2NPC1RAB9AF10PRSS1 | |
| SCHEMBL9257084 | 0.78 | F2 (0.41) | F2F10PRSS1HDAC1ST14 | |
| SCHEMBL9254388 | 0.78 | F2 (0.43) | F2MAPTNPC1RAB9AF10 | |
| SCHEMBL9568559 | 0.78 | F2 (0.41) | F2F10PRSS1HDAC1ST14 | |
| SCHEMBL9257600 | 0.77 | F2 (0.42) | F2F10PRSS1NQO2HDAC1 | |
| Hydrochloric Acid SCHEMBL9254356 | 0.77 | F2 (0.40) | F2F10PRSS1HDAC1ST14 | |
| SCHEMBL9253124 | 0.77 | F2 (0.45) | F2F10PRSS1HDAC1ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |