Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252117 | 0.85 | NR1H4 (0.63) | NR1H4F2TMPRSS15ALPLPRSS1 | |
| SCHEMBL9257707 | 0.83 | F2 (0.44) | MAPTLMNAF2ALDH1A1RAB9A | |
| SCHEMBL9251700 | 0.78 | DGAT1 (0.44) | LMNAF2TMPRSS15RAB9AF10 | |
| SCHEMBL9252726 | 0.77 | TMPRSS15 (0.38) | MAPTF2GAATMPRSS15F10 | |
| SCHEMBL9258255 | 0.74 | MEN1 (0.49) | MAPTLMNAF2ALDH1A1MEN1 | |
| SCHEMBL8948996 | 0.74 | ITGB3 (0.43) | NR1H4F2ITGB3ITGA2B | |
| SCHEMBL15728525 | 0.74 | HCAR2 (0.42) | NR1H4MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL9254605 | 0.74 | ITGB3 (0.41) | ALDH1A1GAATMPRSS15RAB9APOLB | |
| SCHEMBL9254667 | 0.73 | F2 (0.41) | LMNAF2TMPRSS15RAB9ANPC1 | |
| SCHEMBL9253817 | 0.73 | TMPRSS15 (0.38) | F2TMPRSS15F10PRSS1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |