Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 8/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307282 | 0.80 | SMYD3 (0.45) | NPC1RAB9ASMN1; SMN2TSHRSMYD3 | |
| SCHEMBL23193214 | 0.78 | HDAC1 (0.44) | NPC1RAB9ASMN1; SMN2TSHRHDAC1 | |
| SCHEMBL26987352 | 0.78 | MLLT1 (0.43) | NPC1RAB9ASMN1; SMN2TSHRSMYD3 | |
| SCHEMBL14845019 | 0.78 | HDAC1 (0.44) | HDAC1HDAC8HDAC6GSK3BDYRK1A | |
| SCHEMBL2307275 | 0.76 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2TSHRSMYD3 | |
| SCHEMBL19914289 | 0.76 | SMYD3 (0.48) | NPC1RAB9ASMN1; SMN2SMYD3TNKS | |
| SCHEMBL12440555 | 0.76 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2TSHRSMYD3 | |
| SCHEMBL3436851 | 0.76 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2HDAC1HDAC8 | |
| SCHEMBL23505914 | 0.76 | SMYD3 (0.48) | NPC1RAB9ASMN1; SMN2TSHRSMYD3 | |
| SCHEMBL9197574 | 0.75 | FAAH (0.37) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378680-A | Dicarboximides and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | disclosed |
| US-5284821-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| US-5256633-A | Applying pre or postemergence | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| US-5244867-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-14 | — | — | US | disclosed |
| US-5176739-A | Plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1993-01-05 | — | — | US | disclosed |