Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27495720 | 0.92 | TBXAS1 (0.53) | CHRNA7TDP1L3MBTL1FDPSLMNA | |
| SCHEMBL7164881 | 0.89 | TDP1 (0.59) | CHRNA7TDP1L3MBTL1CYP2A6TBXAS1 | |
| SCHEMBL9520426 | 0.89 | TDP1 (0.59) | CHRNA7TDP1L3MBTL1CYP2A6TBXAS1 | |
| SCHEMBL1741942 | 0.86 | TDP1 (0.60) | CHRNA7TDP1L3MBTL1CYP2A6FDPS | |
| Hydrochloric Acid SCHEMBL1740801 | 0.85 | TDP1 (0.58) | CHRNA7TDP1L3MBTL1CYP2A6FDPS | |
| SCHEMBL104468 | 0.85 | CHRNA7 (0.57) | CHRNA7TDP1L3MBTL1CYP2A6LMNA | |
| SCHEMBL23655466 | 0.85 | CHRNA7 (0.57) | CHRNA7TDP1L3MBTL1CYP2A6TBXAS1 | |
| SCHEMBL5016747 | 0.85 | CHRNA7 (0.57) | CHRNA7TDP1L3MBTL1CYP2A6TBXAS1 | |
| SCHEMBL6950753 | 0.82 | TDP1 (0.54) | CHRNA7TDP1L3MBTL1CYP2A6TBXAS1 | |
| SCHEMBL10034621 | 0.82 | TDP1 (0.54) | CHRNA7TDP1L3MBTL1CYP2A6TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1208403-A | Compounds | BRITISH ASTRA PHARMACEUTICALS (GB) | 1999-02-17 | — | — | CN | disclosed |
| US-5428168-A | Substituted butyrolactol ether derivative | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-06-27 | — | — | US | disclosed |
| EP-0527817-A1 | GAMMA-BUTYROLACTOL ETHER DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991017157-A1 | GAMMA-BUTYROLACTOL ETHER DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |