Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 4/20 | 0.37 |
| ▸ | HAT1 | O14929 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628694 | 0.82 | CYP11B1 (0.56) | CYP11B1CYP11B2MAPTPOLBEGLN1 | |
| SCHEMBL9568559 | 0.81 | F2 (0.41) | HDAC1 | |
| SCHEMBL9257084 | 0.81 | F2 (0.41) | HDAC1 | |
| Hydrochloric Acid SCHEMBL9254356 | 0.81 | F2 (0.40) | HDAC1 | |
| Hydrochloric Acid SCHEMBL3628690 | 0.80 | CYP11B1 (0.55) | CYP11B1CYP11B2MAPTPOLBEGLN1 | |
| SCHEMBL1338556 | 0.80 | CYP11B1 (0.60) | CYP11B1CYP11B2MAPTPOLBALDH1A1 | |
| SCHEMBL22756135 | 0.80 | P2RY10 (0.45) | LMNAHDAC6 | |
| SCHEMBL9259632 | 0.80 | CYP11B1 (0.47) | CYP11B1CYP11B2MAPTPOLBEGLN1 | |
| SCHEMBL8863941 | 0.80 | CYP11B1 (0.42) | CYP11B1CYP11B2MAPTPOLBEGLN1 | |
| SCHEMBL9259285 | 0.80 | HRH3 (0.35) | PTGESALDH1A1KDM4ELMNAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |