Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568559 | 0.87 | F2 (0.41) | HDAC1PTGDRCHEK2F2F10 | |
| SCHEMBL9257084 | 0.87 | F2 (0.41) | HDAC1PTGDRCHEK2F2F10 | |
| Hydrochloric Acid SCHEMBL9254356 | 0.86 | F2 (0.40) | HDAC1PTGDRCHEK2F2F10 | |
| SCHEMBL9257792 | 0.80 | CYP11B1 (0.47) | HRH3HDAC1ALDH1A1KDM4ELMNA | |
| SCHEMBL9257104 | 0.78 | HRH3 (0.39) | HRH3HDAC1ADRB2ADRB1HPGD | |
| SCHEMBL9259290 | 0.76 | F2 (0.38) | HDAC1IDO1ALDH1A1KDM4EPTGES | |
| Hydrochloric Acid SCHEMBL9250343 | 0.76 | HDAC1 (0.41) | HRH3HDAC1CNR2PTPN1VDR | |
| SCHEMBL22756135 | 0.76 | P2RY10 (0.45) | LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9248763 | 0.75 | SIRT2 (0.38) | HDAC1CNR2ALDH1A1PTGDRLMNA | |
| SCHEMBL9258085 | 0.74 | TMPRSS15 (0.39) | HPGDALDH1A1KDM4EF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | claimed |
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |