Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR1B | P28222 | 3/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR5A | P47898 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256337 | 0.94 | HTR7 (0.70) | HTR7HSD17B10KMT2ATDP1KDM4E | |
| SCHEMBL5432115 | 0.82 | HTR7 (0.82) | HTR7HSD17B10KMT2ATDP1KDM4E | |
| SCHEMBL9257648 | 0.82 | HTR7 (0.68) | HTR7HSD17B10KMT2ATDP1KDM4E | |
| SCHEMBL9264998 | 0.82 | HTR7 (0.72) | HTR7HSD17B10KMT2ATDP1KDM4E | |
| SCHEMBL4348714 | 0.81 | HTR7 (0.72) | HTR7HSD17B10KMT2ATDP1KDM4E | |
| SCHEMBL10990700 | 0.81 | HTR7 (0.67) | HTR7HSD17B10KMT2ATDP1KDM4E | |
| SCHEMBL10991778 | 0.81 | HTR7 (0.67) | HTR7HSD17B10KMT2ATDP1KDM4E | |
| SCHEMBL10983551 | 0.81 | HTR7 (0.67) | HTR7HSD17B10KMT2ATDP1KDM4E | |
| SCHEMBL3347386 | 0.80 | HTR7 (0.70) | HTR7HSD17B10KMT2ATDP1KDM4E | |
| SCHEMBL27334855 | 0.80 | HTR7 (0.70) | HTR7HSD17B10KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418237-A | Indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-05-23 | — | — | US | disclosed |