Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 11/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258365 | 0.87 | NQO2 (0.38) | TMPRSS15NQO2ITGB3ITGA2BMAPK1 | |
| SCHEMBL9568559 | 0.86 | F2 (0.41) | TMPRSS15ITGB3ITGA2BF2F10 | |
| SCHEMBL9257084 | 0.86 | F2 (0.41) | TMPRSS15ITGB3ITGA2BF2F10 | |
| Hydrochloric Acid SCHEMBL9254356 | 0.85 | F2 (0.40) | TMPRSS15ITGB3ITGA2BF2F10 | |
| SCHEMBL8863950 | 0.82 | TMPRSS15 (0.37) | TMPRSS15NQO2ITGB3ITGA2BMAPT | |
| SCHEMBL9253817 | 0.82 | TMPRSS15 (0.38) | TMPRSS15ITGB3ITGA2BF2F10 | |
| SCHEMBL9251429 | 0.82 | TMPRSS15 (0.36) | TMPRSS15ITGB3ITGA2BF2F10 | |
| SCHEMBL9250408 | 0.81 | CHEK1 (0.38) | TMPRSS15ITGB3ITGA2BMAPTPLAU | |
| SCHEMBL9252726 | 0.81 | TMPRSS15 (0.38) | TMPRSS15NQO2ITGB3ITGA2BMAPT | |
| SCHEMBL9254303 | 0.80 | TMPRSS15 (0.43) | TMPRSS15ITGB3ITGA2BPOLBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |