Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255039 | 0.91 | S1PR1 (0.43) | MAPTL3MBTL1KMT2AMEN1GAA | |
| SCHEMBL9253817 | 0.89 | TMPRSS15 (0.38) | TMPRSS15ITGB3ITGA2BCCNCCDK8 | |
| SCHEMBL9251429 | 0.89 | TMPRSS15 (0.36) | TMPRSS15ITGB3ITGA2BCCNCCDK8 | |
| SCHEMBL9568476 | 0.86 | TMPRSS15 (0.34) | MAPTKMT2AMEN1TMPRSS15ADORA3 | |
| SCHEMBL9254513 | 0.86 | CHEK1 (0.40) | CHEK1L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL9252190 | 0.84 | F10 (0.37) | TMPRSS15ITGB3ITGA2BPLAUCCNC | |
| SCHEMBL9568559 | 0.84 | F2 (0.41) | TMPRSS15ITGB3ITGA2B | |
| SCHEMBL9257084 | 0.84 | F2 (0.41) | TMPRSS15ITGB3ITGA2B | |
| SCHEMBL9258704 | 0.83 | HDAC1 (0.40) | MAPTITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL9254356 | 0.83 | F2 (0.40) | TMPRSS15ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |