Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | DGKA | P23743 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259166 | 0.95 | HTR7 (0.41) | OPRM1OPRD1HTR7ALDH1A1LMNA | |
| SCHEMBL9249976 | 0.89 | PTAFR (0.48) | OPRM1OPRD1ALDH1A1KCNH2KDM4E | |
| SCHEMBL9249978 | 0.89 | PTAFR (0.48) | OPRM1OPRD1ALDH1A1KCNH2KDM4E | |
| SCHEMBL9668898 | 0.87 | PTAFR (0.46) | OPRM1OPRD1ALDH1A1HTR2AHTR1A | |
| SCHEMBL9249230 | 0.84 | PTAFR (0.51) | OPRM1OPRD1ALDH1A1KCNH2KDM4E | |
| SCHEMBL9249240 | 0.84 | PTAFR (0.51) | OPRM1OPRD1ALDH1A1KCNH2KDM4E | |
| SCHEMBL9256690 | 0.81 | PTAFR (0.54) | ALDH1A1KDM4EPTAFR | |
| SCHEMBL9256693 | 0.81 | PTAFR (0.54) | ALDH1A1KDM4EPTAFR | |
| SCHEMBL9257616 | 0.76 | PTAFR (0.57) | ALDH1A1HTR2AHTR1ADRD3SMN1; SMN2 | |
| SCHEMBL9257611 | 0.76 | PTAFR (0.57) | ALDH1A1HTR2AHTR1ADRD3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |