Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DGKA | P23743 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FPR3 | P25089 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258139 | 0.95 | OPRM1 (0.40) | HTR7HRH3PTAFROPRM1OPRD1 | |
| SCHEMBL9668898 | 0.92 | PTAFR (0.46) | HRH3PTAFROPRM1OPRD1ALDH1A1 | |
| SCHEMBL9249230 | 0.89 | PTAFR (0.51) | PTAFROPRM1OPRD1ALDH1A1KCNH2 | |
| SCHEMBL9249240 | 0.89 | PTAFR (0.51) | PTAFROPRM1OPRD1ALDH1A1KCNH2 | |
| SCHEMBL9249978 | 0.84 | PTAFR (0.48) | PTAFROPRM1OPRD1ALDH1A1KCNH2 | |
| SCHEMBL9249976 | 0.84 | PTAFR (0.48) | PTAFROPRM1OPRD1ALDH1A1KCNH2 | |
| SCHEMBL9257616 | 0.82 | PTAFR (0.57) | PTAFRALDH1A1HTR1AHTR2ADRD3 | |
| SCHEMBL9257611 | 0.82 | PTAFR (0.57) | PTAFRALDH1A1HTR1AHTR2ADRD3 | |
| SCHEMBL9668961 | 0.82 | PTAFR (0.57) | PTAFRALDH1A1HTR1AHTR2ADRD3 | |
| SCHEMBL9256732 | 0.79 | PTAFR (0.56) | PTAFRALDH1A1HTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |