Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.72 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.72 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258167 | 1.00 | ESR1 (0.72) | ESR1ESR2HSD17B3NQO2ALDH1A1 | |
| SCHEMBL20534166 | 0.91 | ESR1 (0.61) | ESR1ESR2HSD17B3NQO2ALDH1A1 | |
| SCHEMBL20534163 | 0.91 | ESR1 (0.61) | ESR1ESR2HSD17B3NQO2ALDH1A1 | |
| SCHEMBL574346 | 0.84 | ESR1 (1.00) | ESR1ESR2NQO2ALDH1A1KDM4E | |
| SCHEMBL9113341 | 0.84 | ESR1 (1.00) | ESR1ESR2NQO2ALDH1A1KDM4E | |
| SCHEMBL12459964 | 0.82 | HSD17B3 (0.55) | ESR1ESR2HSD17B3ALDH1A1PTGS1 | |
| SCHEMBL10583351 | 0.82 | HSD17B3 (0.55) | ESR1ESR2HSD17B3ALDH1A1PTGS1 | |
| SCHEMBL20534184 | 0.81 | ESR1 (0.57) | ESR1ESR2HSD17B3PTGS1PTGS2 | |
| SCHEMBL20534185 | 0.81 | ESR1 (0.57) | ESR1ESR2HSD17B3PTGS1PTGS2 | |
| SCHEMBL10647869 | 0.79 | RARB (0.50) | ESR1ESR2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382693-A | Curing agents for epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| WO-1994026690-A1 | BIS(AMINOPHENOXY)-ALPHA-SUBSTITUTED STILBENES, CURABLE MIXTURES WITH EPOXY RESINS AND CURED PRODUCTS | THE DOW CHEMICAL COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5300594-A | Bis(aminophenoxy)-alpha-substituted stilbenes, curable mixtures with epoxy resins and cured products | THE DOW CHEMICAL COMPANY (US) | 1994-04-05 | — | — | US | disclosed |