Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.89 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063203 | 0.89 | ESR1 (0.79) | ESR1RAB9AS1PR1C5AR1LMNA | |
| SCHEMBL9258208 | 0.86 | ESR1 (0.75) | ESR1RAB9AS1PR1ESR2 | |
| SCHEMBL1678584 | 0.85 | ESR1 (0.65) | ESR1RAB9AS1PR1C5AR1LMNA | |
| SCHEMBL7022970 | 0.80 | NR1H2 (0.71) | ESR1RAB9AMAPTNR1I2 | |
| SCHEMBL6302204 | 0.80 | ESR1 (0.88) | ESR1NR1I2 | |
| SCHEMBL8087654 | 0.79 | ESR1 (0.74) | ESR1RAB9AS1PR1C5AR1LMNA | |
| SCHEMBL6301696 | 0.79 | C5AR1 (0.62) | ESR1RAB9AS1PR1C5AR1LMNA | |
| SCHEMBL28722339 | 0.79 | C5AR1 (0.76) | ESR1RAB9AS1PR1C5AR1LMNA | |
| SCHEMBL6295367 | 0.78 | ESR1 (0.88) | ESR1LMNANR1I2 | |
| SCHEMBL9259732 | 0.78 | SMN1; SMN2 (0.61) | ESR1RAB9AS1PR1C5AR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479332-B1 | Diphenyl-methane derivative, pharmaceutical composition and use | EISAI CO LTD (JP) | 1995-06-21 | — | — | EP | disclosed |
| US-5206403-A | Diphenylethylene derivatives, pharmaceutical compositions containing same and treatment methods | EISAI CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| US-5182301-A | Anticoagulants | EISAI CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0479332-A2 | Diphenyl-methane derivative, pharmaceutical composition and use | Eisai Co., Ltd. (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-5103010-A | DIPHENYLETHYLENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND TREATMENT METHOD | EISAI CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0478001-A1 | Benzophenone oxime derivatives, pharmaceutical compositions and use | Eisai Co., Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
| US-5064848-A | Anticoagulants | EISAI CO., LTD. (JP) | 1991-11-12 | — | — | US | disclosed |
| US-5034418-A | Anticoagulants | EISAI CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| US-4978767-A | ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1990-12-18 | — | — | US | disclosed |
| US-4886834-A | ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0238973-A2 | Diphenyl-methane derivative, pharmaceutical composition and use | Eisai Co., Ltd. (JP) | 1987-09-30 | — | — | EP | disclosed |