Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.88 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
| ▸ | RORC | P51449 | 1/20 | 0.64 |
| ▸ | PTGES | O14684 | 3/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 2/20 | 0.58 |
| ▸ | CNR2 | P34972 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593108 | 0.94 | ESR1 (1.00) | ESR1NR3C1NR1I2PTGESALOX5 | |
| SCHEMBL6301442 | 0.90 | ESR1 (0.81) | ESR1NR3C1NR1I2PTGESALOX5 | |
| SCHEMBL5863215 | 0.90 | ESR1 (0.72) | ESR1NR3C1NR1I2RORCPTGES | |
| SCHEMBL5330652 | 0.88 | ESR1 (0.78) | ESR1NR3C1NR1I2RORCPTGES | |
| SCHEMBL5863377 | 0.86 | NR3C1 (0.71) | ESR1NR3C1NR1I2PTGESALOX5 | |
| SCHEMBL5863359 | 0.85 | ESR1 (0.65) | ESR1NR3C1NR1I2RORCPTGES | |
| SCHEMBL3278663 | 0.84 | PTGES (0.84) | ESR1NR3C1NR1I2RORCPTGES | |
| SCHEMBL5863831 | 0.84 | ESR1 (0.63) | ESR1NR3C1NR1I2RORCPTGES | |
| SCHEMBL6295954 | 0.83 | ESR1 (0.71) | ESR1NR3C1NR1I2RORCPTGES | |
| SCHEMBL5863768 | 0.82 | ESR1 (0.60) | ESR1NR3C1NR1I2RORCL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921740-B1 | Electron-receiving compound and thermal recording material | MITSUBISHI PAPER MIILS LTD. (JP) | 2005-07-26 | — | — | US | disclosed |