Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ESR1 | P03372 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464379 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2ESR1LMNAALDH1A1MEN1 | |
| SCHEMBL3452136 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2ESR1LMNAALDH1A1MEN1 | |
| SCHEMBL14349992 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2ESR1LMNAALDH1A1MEN1 | |
| SCHEMBL9258205 | 0.78 | ESR1 (0.89) | ESR1LMNARAB9AS1PR1ESR2 | |
| SCHEMBL4667161 | 0.75 | ESR1 (0.53) | SMN1; SMN2ESR1LMNAALDH1A1MEN1 | |
| SCHEMBL9258208 | 0.73 | ESR1 (0.75) | ESR1RAB9AS1PR1ESR2 | |
| SCHEMBL6297477 | 0.72 | ESR1 (0.61) | ESR1ESR2 | |
| SCHEMBL28302441 | 0.72 | ESR1 (0.60) | SMN1; SMN2ESR1LMNAESR2 | |
| SCHEMBL12879136 | 0.72 | LMNA (0.56) | SMN1; SMN2ESR1LMNAALDH1A1MEN1 | |
| SCHEMBL15336561 | 0.72 | APP (0.44) | ESR1LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479332-B1 | Diphenyl-methane derivative, pharmaceutical composition and use | EISAI CO LTD (JP) | 1995-06-21 | — | — | EP | disclosed |
| US-5206403-A | Diphenylethylene derivatives, pharmaceutical compositions containing same and treatment methods | EISAI CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| US-5182301-A | Anticoagulants | EISAI CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0479332-A2 | Diphenyl-methane derivative, pharmaceutical composition and use | Eisai Co., Ltd. (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-5103010-A | DIPHENYLETHYLENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND TREATMENT METHOD | EISAI CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0478001-A1 | Benzophenone oxime derivatives, pharmaceutical compositions and use | Eisai Co., Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
| US-5064848-A | Anticoagulants | EISAI CO., LTD. (JP) | 1991-11-12 | — | — | US | disclosed |
| US-5034418-A | Anticoagulants | EISAI CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| US-4978767-A | ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1990-12-18 | — | — | US | disclosed |
| US-4954523-A | ANTICOAGULANT | EISAI CO., LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4886834-A | ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0238973-A2 | Diphenyl-methane derivative, pharmaceutical composition and use | Eisai Co., Ltd. (JP) | 1987-09-30 | — | — | EP | disclosed |