SCHEMBL9258245

SCHEMBL9258245

O=[N+]([O-])c1cc(O)ccc1/N=N/c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.56
KMT2A Q03164 8/20 0.56
MAPT P10636 5/20 0.56
ALDH1A1 P00352 4/20 0.56
POLB P06746 2/20 0.56
NPSR1 Q6W5P4 2/20 0.56
LMNA P02545 1/20 0.56
HTT P42858 1/20 0.56
NPC1 O15118 5/20 0.47
EGFR P00533 1/20 0.45
RAB9A P51151 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPK1 P28482 2/20 0.44
RECQL P46063 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
PKM P14618 1/20 0.44
BLM P54132 1/20 0.44
MCL1 Q07820 1/20 0.44
SAE1 Q9UBE0 1/20 0.44
UBA2 Q9UBT2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9506785 0.87 PTPN11 (0.52) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL9506778 0.87 PTPN11 (0.52) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL8081718 0.87 MEN1 (0.53) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL9717757 0.84 MEN1 (0.52) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL9717754 0.84 MEN1 (0.52) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL8078577 0.82 MEN1 (0.48) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL21082742 0.81 MEN1 (0.56) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL10868309 0.81 TDP1 (0.57) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL11043093 0.81 TDP1 (0.57) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL28552829 0.81 L3MBTL1 (0.51) MEN1KMT2AMAPTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0380840-B1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA LTD (JP) 1995-05-17 EP disclosed
US-5187289-A Method of preparing 2-phenyl benzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1993-02-16 US disclosed
US-5104992-A METHOD OF PREPARING 2-PHENYL BENEZOTHRIAZOLES CHEMIPRO KASEI KAISHA, LTD. (JP) 1992-04-14 US disclosed
EP-0380840-A1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-08-08 EP disclosed
EP-0380839-A1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-08-08 EP disclosed