Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266382 | 0.99 | NOD2 (0.43) | NOD2NOD1STSHRH1TACR2 | |
| SCHEMBL13317058 | 0.84 | KDM4E (0.54) | NOD2NOD1STSHRH1TACR2 | |
| SCHEMBL9259877 | 0.83 | HRH1 (0.49) | HRH1TACR2TACR1TP53HSD17B10 | |
| SCHEMBL9260913 | 0.82 | HRH1 (0.51) | NOD2NOD1STSHRH1KDM4E | |
| SCHEMBL9260703 | 0.81 | HRH1 (0.42) | HRH1TACR2TACR1TP53HSD17B10 | |
| SCHEMBL7899281 | 0.81 | HRH1 (0.54) | NOD2NOD1STSHRH1TACR2 | |
| SCHEMBL9268629 | 0.80 | HRH1 (0.45) | HRH1TACR2TACR1TP53HSD17B10 | |
| SCHEMBL7473405 | 0.80 | HRH1 (0.44) | NOD2NOD1STSHRH1TACR2 | |
| SCHEMBL9268701 | 0.80 | HRH1 (0.53) | HRH1TACR2TACR1 | |
| SCHEMBL9262955 | 0.80 | HSD17B10 (0.44) | HRH1TACR2TACR1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380731-A | Antiallergic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0561973-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010491-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-25 | — | — | WO | disclosed |