Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.36 |
| ▸ | RARB | P10826 | 6/20 | 0.36 |
| ▸ | RARG | P13631 | 5/20 | 0.36 |
| ▸ | RXRB | P28702 | 6/20 | 0.34 |
| ▸ | RXRG | P48443 | 6/20 | 0.34 |
| ▸ | RARA | P10276 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191180 | 0.84 | NPC1 (0.34) | MAPTHTTHSD17B10MEN1KMT2A | |
| SCHEMBL8967700 | 0.82 | SLC6A4 (0.37) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL9430441 | 0.82 | — | — | |
| SCHEMBL9430507 | 0.82 | — | — | |
| SCHEMBL8846207 | 0.81 | AKR1C3 (0.33) | — | |
| SCHEMBL9190928 | 0.81 | AKR1C3 (0.33) | — | |
| SCHEMBL9253970 | 0.76 | RXRA (0.49) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL9250431 | 0.76 | RXRA (0.49) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL9193873 | 0.76 | RXRA (0.49) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL9193869 | 0.76 | RXRA (0.49) | RXRARARBRARGRXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459149-A | Penta-2,4-dienamides and use as pesticides | ROUSSEL UCLAF (FR) | 1995-10-17 | — | — | US | disclosed |
| US-5270343-A | Penta-2,4-dienamides and use as pesticides | ROUSSEL UCLAF (FR) | 1993-12-14 | — | — | US | disclosed |