Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 10/20 | 0.36 |
| ▸ | RARB | P10826 | 5/20 | 0.36 |
| ▸ | RARG | P13631 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 4/20 | 0.34 |
| ▸ | RXRG | P48443 | 4/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967739 | 0.89 | NPSR1 (0.36) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9258443 | 0.82 | RXRA (0.36) | RXRARARBRARGALDH1A1MAPT | |
| SCHEMBL9580493 | 0.81 | HPGD (0.41) | SLC6A4SLC6A2SLC6A3ALDH1A1POLB | |
| SCHEMBL9580479 | 0.81 | PYGL (0.32) | SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL9255677 | 0.81 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3ALDH1A1MAPT | |
| SCHEMBL8967113 | 0.77 | RXRA (0.50) | SLC6A4SLC6A2SLC6A3RXRARARB | |
| SCHEMBL8967126 | 0.77 | RXRA (0.50) | SLC6A4SLC6A2SLC6A3RXRARARB | |
| SCHEMBL8967106 | 0.77 | RXRA (0.50) | SLC6A4SLC6A2SLC6A3RXRARARB | |
| SCHEMBL9452367 | 0.77 | SLC6A4 (0.32) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8967144 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553081-B1 | PESTICIDES | ROUSSEL UCLAF (FR) | 1996-02-28 | — | — | EP | disclosed |
| US-5326755-A | Contain cyclopropane ring | ROUSSEL UCLAF | 1994-07-05 | — | — | US | disclosed |