Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15476270 | 0.79 | TDP1 (0.63) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Mannitol SCHEMBL2297640 | 0.76 | LMNA (1.00) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Mannitol SCHEMBL13187369 | 0.76 | LMNA (1.00) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Sorbitol SCHEMBL6817406 | 0.76 | LMNA (1.00) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Mannitol SCHEMBL20594082 | 0.76 | LMNA (1.00) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Mannitol SCHEMBL23066399 | 0.76 | LMNA (1.00) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Sorbitol SCHEMBL763 | 0.76 | LMNA (1.00) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Mannitol SCHEMBL21837180 | 0.76 | LMNA (1.00) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Mannitol SCHEMBL20594083 | 0.76 | LMNA (1.00) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Mannitol SCHEMBL20567656 | 0.76 | LMNA (1.00) | LMNAL3MBTL1TDP1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648203-A1 | NOVEL POLYIODINATED COMPOUNDS, PREPARATION THEREOF AND USE THEREOF AS RADIOLOGICAL CONTRAST AGENTS | GUERBET S.A. (FR) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994021600-A1 | NOVEL POLYIODINATED COMPOUNDS, PREPARATION THEREOF AND USE THEREOF AS RADIOLOGICAL CONTRAST AGENTS | GUERBET S.A. (FR) | 1994-09-29 | — | — | WO | disclosed |