Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 4/20 | 0.52 |
| ▸ | ACHE | P22303 | 7/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737589 | 0.86 | METAP1 (0.52) | METAP1ACHECYP19A1MAPTMAPK1 | |
| SCHEMBL28522885 | 0.78 | METAP1 (0.50) | METAP1ACHECYP19A1MAPTMAPK1 | |
| SCHEMBL6273185 | 0.77 | METAP1 (0.59) | METAP1ACHECYP19A1HTR2CHTR1A | |
| SCHEMBL31374607 | 0.77 | METAP1 (0.55) | METAP1ACHECYP19A1HTR2CHTR1A | |
| SCHEMBL9938389 | 0.77 | METAP1 (0.55) | METAP1ACHECYP19A1HTR2CHTR1A | |
| SCHEMBL6273473 | 0.77 | METAP1 (0.63) | METAP1ACHECYP19A1HTR2CHTR1A | |
| SCHEMBL866816 | 0.76 | METAP1 (0.67) | METAP1ACHECYP19A1HTR2CHTR1A | |
| SCHEMBL6695612 | 0.75 | METAP1 (0.57) | METAP1ACHECYP19A1HTR2CHTR1A | |
| SCHEMBL24506346 | 0.74 | METAP1 (0.55) | METAP1ACHECYP19A1HTR2CHTR1A | |
| SCHEMBL490810 | 0.74 | MAPT (0.70) | METAP1ACHEMAPTMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424308-A | Immunomodulating agents | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-06-13 | — | — | US | disclosed |