Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31460799 | 1.00 | MAPT (0.70) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL947365 | 0.85 | ALDH1A1 (0.55) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2919195 | 0.85 | MAPT (0.51) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29683518 | 0.85 | ALDH1A1 (0.55) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5346346 | 0.84 | MAPT (0.50) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL19417331 | 0.84 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7714519 | 0.83 | ALDH1A1 (0.52) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1000380 | 0.83 | ACHE (0.51) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29476747 | 0.83 | ACHE (0.51) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7950190 | 0.83 | MEN1 (0.58) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11246483-A | — | — | None | — | — | JP | disclosed |
| CN-113004109-A | Asymmetric synthesis method of chiral alpha-hydroxy-beta-ketonic acid ester compound | 浙江工业大学 | 2021-06-22 | — | — | CN | disclosed |
| US-9975848-B2 | Inhibitors of HIV-1 entry and methods of use thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-05-22 | — | — | US | disclosed |
| US-9975848-B2 | Inhibitors of HIV-1 entry and methods of use thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-05-22 | — | — | US | disclosed |
| US-20170233335-A1 | INHIBITORS OF HIV-1 ENTRY AND METHODS OF USE THEREOF | BRYN MAWR COLLEGE | 2017-08-17 | — | — | US | disclosed |
| US-20170233335-A1 | INHIBITORS OF HIV-1 ENTRY AND METHODS OF USE THEREOF | BRYN MAWR COLLEGE | 2017-08-17 | — | — | US | disclosed |
| US-9701684-B2 | Chiral fluorinating reagents | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-9376387-B2 | Oxidisable pyridine derivatives, their preparation and use as anti-alzheimer agents | INSA INST NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2016-06-28 | — | — | US | disclosed |
| WO-2016025681-A1 | INHIBITORS OF HIV-1 ENTRY AND METHODS OF USE THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-02-18 | — | — | WO | disclosed |
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2015-12-10 | — | — | US | disclosed |
| US-7307193-B2 | Catalyst containing a Group VIII metal encapsulated in a polymer that has side chains containing an aromatic substituent; stable even in air, easy to recover, and reusable | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-7307193-B2 | Catalyst containing a Group VIII metal encapsulated in a polymer that has side chains containing an aromatic substituent; stable even in air, easy to recover, and reusable | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| EP-1047674-B1 | PROCESS FOR PRODUCTION OF DONEPEZIL DERIVATIVES | EISAI CO LTD (JP) | 2005-03-30 | — | — | EP | disclosed |
| EP-0991772-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | Biocatalytics, Inc. (US) | 2000-04-12 | — | — | EP | disclosed |
| JP-H11246483-A | PRODUCTION OF ADDITION PRODUCT | TEIKOKU CHEM IND CORP LTD | 1999-09-14 | — | — | JP | disclosed |
| US-5942644-A | Precursors for the production of chiral vicinal aminoalcohols | BIOCATALYTICS, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0738712-B1 | Anti-arrhythmic and cardioprotective substituted indenoylguanidines | HOECHST AG (DE) | 1999-08-18 | — | — | EP | disclosed |
| WO-1998054350-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1998-12-03 | — | — | WO | disclosed |
| US-5733934-A | Antiarrythmic and cardioprotective substituted indenoylguanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-31 | — | — | US | disclosed |
| EP-0738712-A1 | Anti-arrhythmic and cardioprotective substituted indenoylguanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | CBR3, CBR1, CYB5R3 | MAPT 454/4885KDM4E 2033/4885MEN1 4086/4885 |
| US-20170233335-A1 | INHIBITORS OF HIV-1 ENTRY AND METHODS OF USE THEREOF | CD4, CD81, ICAM1 | MAPT 2115/4885KDM4E 2784/4885MEN1 2677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.