Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844722 | 0.89 | ACHE (0.46) | ACHECCR3 | |
| SCHEMBL27347756 | 0.85 | CCR3 (0.44) | ACHECCR3HTR1ASLC6A4 | |
| SCHEMBL27368448 | 0.73 | CCR3 (0.43) | ACHECCR3HTR1ASLC6A4 | |
| SCHEMBL9258755 | 0.70 | CCR3 (0.56) | ACHECCR3HTR1ASLC6A4 | |
| SCHEMBL12424500 | 0.68 | CCR3 (0.73) | ACHECCR3 | |
| SCHEMBL152736 | 0.67 | ACHE (1.00) | ACHECCR3 | |
| SCHEMBL29381887 | 0.66 | CCR3 (0.75) | ACHECCR3 | |
| SCHEMBL7403790 | 0.66 | CCR3 (1.00) | ACHECCR3HTR1ASLC6A4 | |
| SCHEMBL20784864 | 0.66 | HRH3 (0.72) | ACHECCR3 | |
| SCHEMBL9820585 | 0.65 | CCR3 (0.73) | ACHECCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428043-A | Tricyclic-cyclic amines as novel cholinesterase inhibitors | PFIZER INC. (US) | 1995-06-27 | — | — | US | disclosed |