Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 7/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | TTPA | P49638 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 8/20 | 0.36 |
| ▸ | ACHE | P22303 | 8/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250956 | 0.89 | PSEN1 (0.52) | PSEN1ALOX5PTPN1GSTO1TTPA | |
| SCHEMBL9253856 | 0.85 | TTPA (0.50) | PSEN1ALOX5TTPABCHEACHE | |
| SCHEMBL9250207 | 0.81 | PSEN1 (0.47) | PSEN1ALOX5PTPN1GSTO1TTPA | |
| SCHEMBL8539222 | 0.81 | PSEN1 (0.55) | PSEN1ALOX5PTPN1GSTO1TTPA | |
| SCHEMBL8537690 | 0.77 | PTGS1 (0.53) | BCHEACHEPTGS1PTGS2 | |
| SCHEMBL9255238 | 0.76 | TTPA (0.50) | PSEN1ALOX5TTPABCHEACHE | |
| SCHEMBL9250008 | 0.75 | TTPA (0.56) | PSEN1ALOX5TTPABCHEACHE | |
| SCHEMBL9250111 | 0.73 | TTPA (0.51) | PSEN1ALOX5TTPABCHEACHE | |
| SCHEMBL8420875 | 0.72 | PSEN1 (0.65) | PSEN1ALOX5PTPN1GSTO1TTPA | |
| SCHEMBL16247652 | 0.72 | PSEN1 (0.56) | PSEN1PTPN1GSTO1TTPABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |
| EP-0587499-A1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR ET COMPAGNIE (FR) | 1994-03-16 | — | — | EP | disclosed |