Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558987 | 0.82 | ITGB3 (0.64) | ITGB3ITGA2BF2 | |
| SCHEMBL9262498 | 0.80 | F2 (0.45) | ITGB3ITGA2BKLK5F2KLK1 | |
| SCHEMBL9558988 | 0.80 | ITGB3 (0.64) | ITGB3ITGA2BF2 | |
| SCHEMBL9264956 | 0.79 | ITGB3 (0.45) | ITGB3ITGA2BKLK5F2 | |
| SCHEMBL9426023 | 0.78 | KLK5 (0.45) | ITGB3ITGA2BKLK5F2KLK1 | |
| SCHEMBL9558976 | 0.78 | ITGB3 (0.66) | ITGB3ITGA2BF2 | |
| SCHEMBL9263614 | 0.74 | KLK5 (0.40) | ITGB3ITGA2BKLK5F2KLK1 | |
| SCHEMBL7352353 | 0.74 | ITGB3 (0.66) | ITGB3ITGA2BF2 | |
| SCHEMBL7344449 | 0.74 | ITGB3 (0.66) | ITGB3ITGA2BF2 | |
| SCHEMBL7361739 | 0.73 | CYP2C19 (0.67) | KLK5F2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |