Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | FNTA | P49354 | 1/20 | 0.59 |
| ▸ | FNTB | P49356 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972937 | 0.85 | PARP1 (0.58) | CYP2C19RAB9AHTTKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7351844 | 0.84 | PARP1 (0.57) | CYP2C19RAB9AHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7824367 | 0.79 | RAB9A (0.72) | CYP2C19RAB9AHTTKDM4ESMN1; SMN2 | |
| SCHEMBL19420106 | 0.79 | HTT (0.72) | CYP2C19RAB9AHTTKDM4ESMN1; SMN2 | |
| SCHEMBL9572188 | 0.78 | KLK5 (0.50) | RAB9ASMN1; SMN2POLBGAAMAPT | |
| SCHEMBL9558987 | 0.78 | ITGB3 (0.64) | RAB9ALMNAF2 | |
| SCHEMBL3917111 | 0.78 | RAB9A (1.00) | CYP2C19RAB9AHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7823539 | 0.78 | MAPT (1.00) | CYP2C19RAB9AHTTKDM4ESMN1; SMN2 | |
| SCHEMBL9426346 | 0.76 | F2 (0.43) | CYP2C19RAB9AHTTKDM4ESMN1; SMN2 | |
| SCHEMBL9558988 | 0.76 | ITGB3 (0.64) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550159-A | Peptide mimics useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5453440-A | Amidine functional group on benzene ring, anticoagulants | G. D. SEARLE & CO. (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1993018058-A1 | PEPTIDES MIMICS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-09-16 | — | — | WO | disclosed |