Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.72 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.72 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.72 |
| ▸ | PDE5A | O76074 | 10/20 | 0.72 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258758 | 0.86 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7400585 | 0.84 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7451032 | 0.74 | PDE5A (1.00) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7395897 | 0.72 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7446384 | 0.71 | PDE5A (1.00) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7451337 | 0.70 | PDE5A (1.00) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7397785 | 0.69 | GRIN1 (0.53) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7399392 | 0.64 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7400203 | 0.64 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7403404 | 0.64 | ALDH1A1 (0.57) | PDE4APDE4BPDE4CPDE4DPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409934-A | Antiallergens | BEECHAM GROUP P.L.C. (GB) | 1995-04-25 | — | — | US | disclosed |