Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HPN | P05981 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257981 | 0.98 | F2 (0.43) | F2KLK5CYP2C19F7GAA | |
| SCHEMBL9258823 | 0.84 | GAA (0.35) | CYP2C19GAAMAPTRAB9A | |
| SCHEMBL9257997 | 0.82 | GAA (0.37) | CYP2C19GAAMAPTRAB9A | |
| SCHEMBL9262498 | 0.82 | F2 (0.45) | F2KLK5CYP2C19F7GAA | |
| SCHEMBL9264866 | 0.76 | F2 (0.42) | F2KLK5CYP2C19F7F10 | |
| SCHEMBL9264977 | 0.75 | F2 (0.41) | F2KLK5CYP2C19F7RAB9A | |
| SCHEMBL9263614 | 0.74 | KLK5 (0.40) | F2KLK5F7F10PRSS1 | |
| SCHEMBL9258794 | 0.74 | F2 (0.44) | F2KLK5CYP2C19F7GAA | |
| SCHEMBL7352341 | 0.74 | F7 (0.47) | F2F7F10PRSS1PLAU | |
| SCHEMBL7344436 | 0.74 | F7 (0.47) | F2F7F10PRSS1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |