Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 4/20 | 0.39 |
| ▸ | HPN | P05981 | 4/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258807 | 0.83 | GAA (0.38) | CYP2C19GAAMAPTKDM4EHTT | |
| SCHEMBL9257981 | 0.76 | F2 (0.43) | F2CYP2C19KLK5GAAMAPT | |
| SCHEMBL7361739 | 0.74 | CYP2C19 (0.67) | F2CYP2C19KLK5GAAMAPT | |
| SCHEMBL9258802 | 0.74 | F2 (0.45) | F2CYP2C19KLK5GAAMAPT | |
| SCHEMBL9262498 | 0.74 | F2 (0.45) | F2CYP2C19KLK5GAAMAPT | |
| SCHEMBL6984397 | 0.73 | ITGB3 (0.46) | F2SMN1; SMN2 | |
| SCHEMBL9572188 | 0.72 | KLK5 (0.50) | F2KLK5GAAMAPTSMN1; SMN2 | |
| SCHEMBL9264866 | 0.72 | F2 (0.42) | F2CYP2C19KLK5PLAUHPN | |
| SCHEMBL6983967 | 0.70 | ITGB3 (0.51) | F2MAPTPLAUF7KDM4E | |
| SCHEMBL9264977 | 0.70 | F2 (0.41) | F2CYP2C19KLK5F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |