Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9283475 | 0.87 | ADRB2 (0.56) | TOP2ATOP2BKCNH2GSK3BALDH1A1 | |
| SCHEMBL6645463 | 0.86 | TOP2A (0.60) | TOP2ATOP2BKCNH2GSK3BALDH1A1 | |
| SCHEMBL9264378 | 0.85 | KDM4E (0.55) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL3400695 | 0.85 | TOP2A (0.61) | TOP2ATOP2BKCNH2GSK3BALDH1A1 | |
| SCHEMBL29463823 | 0.81 | TOP2A (0.71) | TOP2ATOP2BKCNH2GSK3BALDH1A1 | |
| SCHEMBL500719 | 0.81 | TOP2A (0.71) | TOP2ATOP2BKCNH2GSK3BALDH1A1 | |
| SCHEMBL13585809 | 0.80 | TOP2A (0.58) | TOP2ATOP2BKCNH2GSK3BALDH1A1 | |
| SCHEMBL13581382 | 0.80 | KCNH2 (0.55) | TOP2ATOP2BKCNH2GSK3BALDH1A1 | |
| SCHEMBL3136282 | 0.80 | TOP2A (0.66) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL10511115 | 0.80 | TOP2A (0.69) | TOP2ATOP2BKCNH2GSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468742-A | Antibacterial agents, feed additives | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-21 | — | — | US | disclosed |