Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.58 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645463 | 0.92 | TOP2A (0.60) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL14143614 | 0.91 | KCNH2 (0.63) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL13581382 | 0.88 | KCNH2 (0.55) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL14143613 | 0.88 | KCNH2 (0.62) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL10571331 | 0.84 | KDM4E (0.60) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL4369417 | 0.84 | LMNA (0.63) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL4368116 | 0.83 | ALDH1A1 (0.66) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL3400695 | 0.83 | TOP2A (0.61) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL10470855 | 0.82 | TOP2A (0.63) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL10572826 | 0.82 | ALDH1A1 (0.75) | TOP2ATOP2BKCNH2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7626032-B2 | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments | WOCKHARDT LIMITED (IN) | 2009-12-01 | — | — | US | disclosed |
| US-20080214608-A1 | New generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments | WOCKHARDT LIMITED | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214608-A1 | New generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments | ABCG2, CYP3A7, UGT1A7 | TOP2A 292/4885TOP2B 815/4885KCNH2 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.