Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264408 | 0.86 | NPC1 (0.39) | RXRARXRBMRGPRX4KDM4ENPC1 | |
| SCHEMBL9251869 | 0.85 | CYP26A1 (0.49) | RXRARXRBNR1H4MRGPRX4CYP26A1 | |
| SCHEMBL9260238 | 0.84 | RXRA (0.45) | RXRARXRBNR1H4NPC1RAB9A | |
| SCHEMBL9259656 | 0.84 | CYP26A1 (0.48) | RXRARXRBNR1H4MRGPRX4CYP26A1 | |
| SCHEMBL9258204 | 0.84 | CYP26A1 (0.48) | RXRARXRBNR1H4MRGPRX4CYP26A1 | |
| SCHEMBL9262883 | 0.75 | HDAC6 (0.43) | RXRARXRBNR1H4PLA2G4BRXRG | |
| SCHEMBL9261977 | 0.75 | HDAC6 (0.46) | NR1H4NPC1RAB9AMAPT | |
| SCHEMBL9259665 | 0.74 | CYP26A1 (0.38) | RXRARXRBNR1H4MRGPRX4CYP26A1 | |
| SCHEMBL9258210 | 0.74 | CYP26A1 (0.38) | RXRARXRBNR1H4MRGPRX4CYP26A1 | |
| SCHEMBL9255150 | 0.74 | GAA (0.46) | CYP26A1CYP3A4CYP26B1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432195-A | Anticholesterol | NIPPON SHINYAKU COMPANY LIMITED (JP) | 1995-07-11 | — | — | US | claimed |
| US-5432195-A | Anticholesterol | NIPPON SHINYAKU COMPANY LIMITED (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0601181-A1 | BENZOFURAN DERIVATIVE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1994-06-15 | — | — | EP | disclosed |