Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251869 | 0.99 | CYP26A1 (0.49) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL9258204 | 0.98 | CYP26A1 (0.48) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL9255150 | 0.88 | GAA (0.46) | CYP26A1CYP3A4CYP26B1POLBNPC1 | |
| SCHEMBL9259665 | 0.88 | CYP26A1 (0.38) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL9258210 | 0.88 | CYP26A1 (0.38) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL9258905 | 0.84 | RXRA (0.46) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL9255197 | 0.83 | NPC1 (0.38) | RXRARXRBKDM4EPOLBMAPK1 | |
| SCHEMBL9259950 | 0.83 | NR4A2 (0.47) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL9254836 | 0.82 | RXRA (0.48) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL9263173 | 0.81 | RXRA (0.47) | CYP26A1CYP3A4CYP26B1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432195-A | Anticholesterol | NIPPON SHINYAKU COMPANY LIMITED (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0601181-A1 | BENZOFURAN DERIVATIVE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1994-06-15 | — | — | EP | disclosed |