Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259582 | 0.91 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9260677 | 0.89 | ALOX5 (0.61) | ALOX5 | |
| SCHEMBL9261263 | 0.88 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9267540 | 0.81 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9136516 | 0.80 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9136514 | 0.80 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9285925 | 0.79 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9390469 | 0.79 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL29519211 | 0.79 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9300407 | 0.79 | ALOX5 (1.00) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428060-A | Useful as antiasthamatic, antiallergic, antiinflammatory and cytoprotective agent | MERCK FROSST CANADA, INC. (CA) | 1995-06-27 | — | — | US | claimed |
| US-5428060-A | Useful as antiasthamatic, antiallergic, antiinflammatory and cytoprotective agent | MERCK FROSST CANADA, INC. (CA) | 1995-06-27 | — | — | US | disclosed |
| WO-1994005657-A1 | HETEROARYLNAPHTHALENE HYDROXY ACIDS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1994-03-17 | — | — | WO | disclosed |
| US-5252599-A | Antiasthma, antiallergens, antiinflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1993-10-12 | — | — | US | disclosed |