Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | PRNP | P04156 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ILK | Q13418 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL27710702 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL16835595 | 0.74 | IKBKB (0.34) | TSHR | |
| SCHEMBL6980098 | 0.73 | HTR2C (0.53) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL2747413 | 0.73 | PSMB8 (0.41) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL2623678 | 0.73 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL25366862 | 0.72 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL31595929 | 0.72 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL5892826 | 0.72 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL303457 | 0.72 | XIAP (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL30618206 | 0.72 | TP53 (0.38) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043891-C | Fluorobenzothiazolyloxyacetamides | BAYER AG (DE) | 1999-06-30 | — | — | CN | disclosed |
| US-5442074-A | Sulfonyl containing fluorobenzothiazole as chemical intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1995-08-15 | — | — | US | disclosed |
| US-5356864-A | New herbicidal fluorobenzothiazolyloxyacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| CN-1087903-A | Fluoro benzothiazole oxygen yl acetamide | BAYER AG (DE) | 1994-06-15 | — | — | CN | disclosed |
| EP-0588183-A1 | Fluoro benzothiazolyloxyacetamide | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |