Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6475965 | 0.98 | LMNA (0.54) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL8194671 | 0.84 | LMNA (0.56) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL10945163 | 0.84 | CA12 (0.56) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL10949073 | 0.84 | CA12 (0.56) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL5683316 | 0.82 | CYP1A2 (0.53) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL940578 | 0.82 | LMNA (0.65) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL30582428 | 0.82 | LMNA (0.65) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL868005 | 0.81 | CYP1A2 (0.59) | LMNACYP1A2CYP3A4MAOACA12 | |
| Hydrochloric Acid SCHEMBL11617136 | 0.81 | CYP1A2 (0.51) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL11619777 | 0.81 | LMNA (0.51) | LMNACYP1A2CYP3A4MAOACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029897-A1 | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS | G.D. SEARLE & CO. (US) | 1995-11-09 | — | — | WO | disclosed |