Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27783042 | 0.98 | CYP1A2 (0.57) | CYP1A2LMNACYP3A4MAOACA12 | |
| Acetic Acid SCHEMBL5925599 | 0.95 | CYP1A2 (0.54) | CYP1A2LMNACYP3A4MAOACA12 | |
| SCHEMBL11686826 | 0.87 | ALDH1A1 (0.54) | CYP1A2LMNACYP3A4MAOAESR1 | |
| SCHEMBL5076653 | 0.87 | ALDH1A1 (0.61) | CYP1A2LMNACYP3A4MAOACA12 | |
| SCHEMBL30582428 | 0.84 | LMNA (0.65) | CYP1A2LMNACYP3A4MAOACA12 | |
| SCHEMBL940578 | 0.84 | LMNA (0.65) | CYP1A2LMNACYP3A4MAOACA12 | |
| SCHEMBL3256021 | 0.84 | CA12 (0.61) | CYP1A2LMNACYP3A4MAOACA12 | |
| SCHEMBL9701917 | 0.83 | ESR1 (0.50) | CYP1A2LMNACYP3A4ESR1ALDH1A1 | |
| SCHEMBL868290 | 0.83 | LMNA (0.62) | CYP1A2LMNACYP3A4MAOACA12 | |
| SCHEMBL6301547 | 0.83 | CA12 (0.59) | CYP1A2LMNACYP3A4MAOACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773278-A | Quinazoline compound and application thereof in antivirus | 苏州大学 | 2022-07-22 | — | — | CN | claimed |
| US-20060110743-A1 | Drug evolution: drug design at hot spots | KONISHI YASUO | 2006-05-25 | — | — | US | claimed |
| WO-2002095393-A2 | DRUG EVOLUTION: DRUG DESIGN AT HOT SPOTS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2002-11-28 | — | — | WO | claimed |
| EP-3837008-B1 | SUBSTITUTED BENZAMIDES AND THEIR USE IN THERAPY | PHARMACYL AB (SE) | 2025-09-24 | — | — | EP | disclosed |
| EP-4559903-A1 | PRODUCTION METHOD FOR TAFAMIDIS OR SALT THEREOF | Shiratori Pharmaceutical Co., Ltd. (JP) | 2025-05-28 | — | — | EP | disclosed |
| CN-112703036-B | Substituted benzamides and their use in therapy | 法玛西尔有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-119585243-A | Process for producing cloxazoic acid or salt thereof | 白鸟制药株式会社 | 2025-03-07 | — | — | CN | disclosed |
| US-20250064761-A1 | SUBSTITUTED BENZAMIDES AND THEIR USE IN THERAPY | PHARMACYL AB (SE) | 2025-02-27 | — | — | US | disclosed |
| CN-112770736-B | Novel medical treatment of pathological inflammation | 法玛西尔有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-114773278-B | Quinazoline compound and application thereof in antiviral | 苏州大学 | 2024-07-30 | — | — | CN | disclosed |
| EP-3836912-B1 | COMBINATIONS OF SUBSTITUTED BENZAMIDES AND 5-ASA AGENTS | PHARMACYL AB (SE) | 2024-05-01 | — | — | EP | disclosed |
| US-3971771-A | DYES FOR POLYESTERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3971738-A | Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3971740-A | DYES FOR POLYESTER FIBERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3964862-A | Process for dyeing and printing textile materials of synthetic organic fibers | CIBA-GEIGY AG (CH) | 1976-06-22 | — | — | US | disclosed |
| US-3954398-A | Polyester fibers dyed with a disazo disperse dyestuff | CIBA-GEIGY AG (CH) | 1976-05-04 | — | — | US | disclosed |
| US-3945991-A | Heterocyclic azo compounds containing a quaternated hydrazide group | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |
| US-3945989-A | Fluoro triazine containing water insoluble azo dyestuff | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |
| US-3943120-A | WATER INSOLUBLE | CIBA-GEIGY AG (CH) | 1976-03-09 | — | — | US | disclosed |
| US-3933786-A | Heterocyclic-azo-phenyl compounds containing a styrl group | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250064761-A1 | SUBSTITUTED BENZAMIDES AND THEIR USE IN THERAPY | BRD4, SI, BRD7 | CYP1A2 644/4885LMNA 2473/4885CYP3A4 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.