SCHEMBL9258980

SCHEMBL9258980

CSc1ccc(C(=O)CCCCCCn2ccnc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 12/20 0.70
QPCT Q16769 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10567974 0.83 QPCT (0.50) TBXAS1QPCT
SCHEMBL10567981 0.83 QPCT (0.50) TBXAS1QPCT
SCHEMBL9266704 0.82 TBXAS1 (0.70) TBXAS1QPCT
SCHEMBL9264092 0.82 TBXAS1 (0.70) TBXAS1QPCT
SCHEMBL9268521 0.81 TBXAS1 (0.69) TBXAS1
SCHEMBL11262682 0.80 TBXAS1 (0.67) TBXAS1QPCT
SCHEMBL7196791 0.79 L3MBTL1 (0.55)
SCHEMBL6948566 0.79 TBXAS1 (0.68) TBXAS1
SCHEMBL6947605 0.78 TBXAS1 (0.67) TBXAS1QPCT
SCHEMBL6943143 0.78 TBXAS1 (0.67) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274867-A2 Pharmaceutically active compounds SCHERING CORPORATION (US) 1988-07-20 EP claimed
US-5459144-A Enterovirus and rhinovirus antiviral, antiinflammatory and antagonist of platelet activating factor SCHERING CORPORATION (US) 1995-10-17 US disclosed
US-5272167-A Pharmaceutically active compounds SCHERING CORPORATION (US) 1993-12-21 US disclosed
EP-0560407-A1 Pharmaceutically active compounds SCHERING CORPORATION (US) 1993-09-15 EP disclosed
WO-1991000858-A1 PHARMACEUTICALLY ACTIVE COMPOUNDS SCHERING CORPORATION (US) 1991-01-24 WO disclosed
EP-0407217-A1 Pharmaceutically active compounds SCHERING CORPORATION (US) 1991-01-09 EP disclosed
US-4851423-A Pharmaceutically active compounds SCHERING CORPORATION (US) 1989-07-25 US disclosed
EP-0274867-A2 Pharmaceutically active compounds SCHERING CORPORATION (US) 1988-07-20 EP disclosed