Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260772 | 0.79 | SOAT1 (0.70) | SOAT1PPARGPPARAPPARD | |
| SCHEMBL9258955 | 0.76 | CNR2 (0.53) | SOAT1PPARGPPARAHDAC6HDAC1 | |
| SCHEMBL9252062 | 0.76 | SOAT1 (0.48) | SOAT1PPARGPPARAHDAC6HDAC1 | |
| SCHEMBL9260818 | 0.74 | SOAT1 (0.43) | SOAT1PPARGPPARAHDAC6HDAC1 | |
| SCHEMBL8768874 | 0.74 | PPARG (0.46) | SOAT1PPARGPPARAHDAC6HDAC1 | |
| SCHEMBL8925558 | 0.74 | PPARA (0.40) | SOAT1PPARGPPARAHDAC6HDAC1 | |
| SCHEMBL9784524 | 0.73 | SOAT1 (0.51) | SOAT1PPARGPPARAHDAC6HDAC1 | |
| SCHEMBL9252884 | 0.73 | HDAC1 (0.46) | SOAT1PPARGPPARAHDAC6HDAC1 | |
| SCHEMBL9253807 | 0.72 | TSHR (0.54) | SOAT1PPARGPPARAHDAC6HDAC1 | |
| SCHEMBL9248994 | 0.72 | HDAC6 (0.56) | SOAT1HDAC6HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422373-A | An alkoxybenzyl-alkylene-arylurea anticholesterol, antilipemic agents and enzyme inhibitors | BURROUGHS WELLCOME CO. (US) | 1995-06-06 | — | — | US | disclosed |