Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925558 | 0.91 | PPARA (0.40) | PPARGPPARAPPARDSOAT1EGFR | |
| SCHEMBL8767697 | 0.84 | PPARG (0.46) | PPARGPPARAPPARDSOAT1EGFR | |
| SCHEMBL8925673 | 0.76 | HDAC1 (0.44) | PPARGPPARAPPARDSOAT1EGFR | |
| SCHEMBL8767912 | 0.74 | SOAT1 (0.48) | PPARGPPARAPPARDSOAT1EGFR | |
| SCHEMBL9259009 | 0.74 | SOAT1 (0.48) | PPARGPPARAPPARDSOAT1HDAC3 | |
| SCHEMBL8768643 | 0.72 | ALDH1A1 (0.46) | PPARGPPARASOAT1EGFR | |
| SCHEMBL8768938 | 0.69 | PPARA (0.54) | PPARGPPARAPPARDSOAT1HDAC3 | |
| SCHEMBL8768759 | 0.68 | PPARA (0.53) | PPARGPPARAPPARDSOAT1HDAC3 | |
| SCHEMBL8803723 | 0.68 | SOAT1 (0.47) | PPARGPPARAPPARDSOAT1EGFR | |
| SCHEMBL8768899 | 0.68 | PPARA (0.57) | PPARGPPARAPPARDSOAT1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |