⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1264248 | 0.69 | — | — | |
| SCHEMBL1431693 | 0.69 | THRB (0.40) | — | |
| SCHEMBL10948246 | 0.67 | — | — | |
| SCHEMBL1926899 | 0.67 | — | — | |
| Thiourea SCHEMBL7984306 | 0.65 | — | — | |
| Thiourea SCHEMBL11645081 | 0.65 | TSHR (0.60) | — | |
| SCHEMBL7529551 | 0.65 | — | — | |
| SCHEMBL2234058 | 0.65 | — | — | |
| SCHEMBL6501821 | 0.65 | — | — | |
| SCHEMBL760725 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1700911-A | Combination drug | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-5420122-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0272455-B1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-10 | — | — | EP | disclosed |
| US-5138064-A | Chemical intermediate for penicillin derivative | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-4921852-A | CARBAPENICILLINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0272455-A1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |