Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 5/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.30 |
| ▸ | TACR1 | P25103 | 2/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926339 | 0.90 | NOTUM (0.34) | CACNA1HNOTUMKIT | |
| SCHEMBL854530 | 0.90 | NOTUM (0.33) | CACNA1HNOTUMKIT | |
| SCHEMBL855815 | 0.90 | CACNA1H (0.33) | CACNA1HKIT | |
| SCHEMBL854962 | 0.89 | NOTUM (0.33) | CACNA1HNOTUMKIT | |
| SCHEMBL855479 | 0.87 | NOTUM (0.37) | NOTUMKITTACR1RXRARXRB | |
| SCHEMBL854897 | 0.86 | RXRA (0.31) | NOTUMKITTACR1RXRARXRB | |
| SCHEMBL855913 | 0.86 | NOTUM (0.36) | NOTUMKITTACR1RXRARXRB | |
| SCHEMBL861504 | 0.79 | NOTUM (0.40) | NOTUMKIT | |
| SCHEMBL854638 | 0.79 | NOTUM (0.35) | NOTUMKIT | |
| SCHEMBL854960 | 0.79 | NOTUM (0.35) | NOTUMKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9055749-B2 | Insecticidal arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| EP-2432762-B1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2242739-B1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2014-11-12 | — | — | EP | disclosed |
| US-20140024680-A1 | Insecticidal Arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-23 | — | — | US | disclosed |
| US-8410141-B2 | Insecticidal arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-8304371-B2 | Insecticidal arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20120108635-A1 | Insecticidal Arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2012-05-03 | — | — | US | disclosed |
| US-20110003690-A1 | INSECTICIDAL ARYLPYRROLINES | BAY CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| EP-2242739-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009097992-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003690-A1 | INSECTICIDAL ARYLPYRROLINES | DDT, ACHE, CYP1A2 | CACNA1H 2052/4885NOTUM 748/4885KIT 3844/4885 |
| US-20140024680-A1 | Insecticidal Arylpyrrolines | DDT, ACHE, CYP1A2 | CACNA1H 2113/4885NOTUM 803/4885KIT 3893/4885 |
| US-20120108635-A1 | Insecticidal Arylpyrrolines | DDT, ACHE, CYP1A2 | CACNA1H 2113/4885NOTUM 803/4885KIT 3893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.