Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 9/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427451 | 0.90 | TTPA (0.53) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL9254414 | 0.90 | PSEN1 (0.41) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL9255031 | 0.86 | PSEN1 (0.50) | TTPAALOX5PSEN1PTGS1PTGS2 | |
| SCHEMBL9250207 | 0.86 | PSEN1 (0.47) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL9255238 | 0.84 | TTPA (0.50) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL9256806 | 0.84 | PTGS1 (0.49) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9250373 | 0.84 | PSEN1 (0.41) | TTPAALOX5PSEN1PTGS1PTGS2 | |
| SCHEMBL9254582 | 0.84 | PSEN1 (0.44) | TTPAALOX5PSEN1PTGS1PTGS2 | |
| SCHEMBL9268645 | 0.83 | TTPA (0.43) | TTPAALOX5KMT2AMEN1PDE4A | |
| SCHEMBL9250567 | 0.83 | BCHE (0.44) | TTPAALOX5KMT2AMEN1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |
| EP-0587499-A1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR ET COMPAGNIE (FR) | 1994-03-16 | — | — | EP | disclosed |