Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9254256 | 0.99 | TSHR (0.67) | TSHRHSD17B10HPGDTP53GAA | |
| SCHEMBL9252550 | 0.86 | TP53 (0.67) | TSHRHSD17B10HPGDTP53GAA | |
| SCHEMBL9258387 | 0.85 | TP53 (0.62) | TSHRHSD17B10HPGDTP53GAA | |
| SCHEMBL9256828 | 0.81 | TSHR (0.68) | TSHRHSD17B10HPGDTP53GAA | |
| SCHEMBL9251339 | 0.78 | HPGD (0.49) | TSHRHSD17B10HPGDTP53GAA | |
| Hydrochloric Acid SCHEMBL9254302 | 0.77 | HPGD (0.48) | TSHRHSD17B10HPGDTP53GAA | |
| SCHEMBL9257817 | 0.76 | HPGD (0.43) | TSHRHSD17B10HPGDTP53GAA | |
| Hydrochloric Acid SCHEMBL7276941 | 0.73 | PPARD (0.38) | TSHRHSD17B10HPGDTP53GAA | |
| Hydrochloric Acid SCHEMBL7272915 | 0.72 | ROCK2 (0.42) | TSHRHSD17B10HPGDTP53GAA | |
| Hydrochloric Acid SCHEMBL7275730 | 0.72 | CYP2C19 (0.46) | GAASMN1; SMN2RAB9ACYP2C9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | claimed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | claimed |