Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259216 | 0.81 | TSHR (0.68) | TSHRHSD17B10HPGDTP53GAA | |
| Hydrochloric Acid SCHEMBL9254256 | 0.80 | TSHR (0.67) | TSHRHSD17B10HPGDTP53GAA | |
| SCHEMBL9252550 | 0.79 | TP53 (0.67) | TSHRHSD17B10HPGDTP53GAA | |
| SCHEMBL9253975 | 0.78 | HPGD (0.49) | TSHRHSD17B10HPGDTP53GAA | |
| SCHEMBL6324652 | 0.72 | HPGD (0.63) | TSHRHSD17B10HPGDTP53GAA | |
| SCHEMBL3628694 | 0.72 | CYP11B1 (0.56) | TSHRHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL8408009 | 0.71 | KCNA5 (0.56) | TSHRHPGDSMN1; SMN2USP2CYP1A2 | |
| Hydrochloric Acid SCHEMBL3628690 | 0.71 | CYP11B1 (0.55) | TSHRHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL7153866 | 0.70 | ALDH1A1 (0.62) | TSHRMAPTAOC3ALDH1A1RAB9A | |
| SCHEMBL7275473 | 0.70 | CYP11B1 (0.42) | MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |