Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868519 | 0.82 | EPHX2 (0.43) | GSK3BEPHX2KIF11CTBP2CYP2A6 | |
| SCHEMBL7412854 | 0.79 | MEN1 (0.63) | GSK3BEPHX2KIF11CTBP2CYP2A6 | |
| SCHEMBL262672 | 0.77 | CYP2C19 (0.47) | KIF11HTTMAPTALDH1A1MEN1 | |
| SCHEMBL8224210 | 0.76 | KIF11 (0.52) | GSK3BEPHX2KIF11CYP2A6CA1 | |
| SCHEMBL10347288 | 0.76 | MIF (0.50) | GSK3BCYP19A1HTTMAPTALDH1A1 | |
| SCHEMBL6245761 | 0.74 | KIF11 (0.50) | EPHX2KIF11CYP2A6MLYCDCA1 | |
| SCHEMBL28846139 | 0.73 | KIF11 (0.48) | EPHX2KIF11CYP19A1MLYCDCA1 | |
| SCHEMBL12004125 | 0.72 | KIF11 (0.52) | KIF11CYP19A1MLYCDCA1CA2 | |
| SCHEMBL11622599 | 0.71 | KIF11 (0.47) | KIF11CYP2A6CYP19A1PTPN5MEN1 | |
| SCHEMBL31294502 | 0.71 | KIF11 (0.47) | GSK3BEPHX2KIF11CTBP2MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428160-A | Condensation of imidazole derivative with cyano- or halo-substituted benzene derivative containing leaving group esterified with carboxylic or sulfonic acid | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| US-4889861-A | Substituted imidazo[1,5-a]pyridine derivatives and other substituted bicyclic derivatives and their use as aromatase inhibitors | CIBA-GEIGY CORP. (US) | 1989-12-26 | — | — | US | disclosed |
| US-4728645-A | THROMBOXANE SYNTHETASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1988-03-01 | — | — | US | disclosed |