Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPNS2 | Q8IVW8 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | DVL1 | O14640 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250797 | 0.93 | FFAR1 (0.43) | SPNS2FFAR1CASP3SENP8SENP7 | |
| SCHEMBL9251417 | 0.87 | FFAR1 (0.40) | SPNS2FFAR1CASP3SENP8SENP7 | |
| SCHEMBL9251212 | 0.87 | HRH3 (0.42) | SPNS2CASP3SENP8SENP7SENP6 | |
| SCHEMBL9251406 | 0.86 | RXRA (0.44) | FFAR1CASP3SENP8SENP7SENP6 | |
| SCHEMBL9248373 | 0.86 | FFAR1 (0.40) | SPNS2FFAR1CASP3SENP8SENP7 | |
| SCHEMBL9258269 | 0.86 | ITGB3 (0.52) | FFAR1CASP3SENP8SENP7SENP6 | |
| SCHEMBL9251393 | 0.86 | ITGB3 (0.52) | FFAR1CASP3SENP8SENP7SENP6 | |
| SCHEMBL9256853 | 0.85 | FFAR1 (0.43) | FFAR1CASP3SENP8SENP7SENP6 | |
| SCHEMBL9257985 | 0.85 | BRD4 (0.41) | FFAR1CASP3SENP8SENP7SENP6 | |
| SCHEMBL9254431 | 0.84 | AKT2 (0.44) | FFAR1CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |